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Na+ Na+ K+ K+ Renin Solute carrier family 12 member 3 Sodium/potassium- transporting ATPase subunit alpha-1 Sodium/potassium- transporting ATPase subunit alpha-2 Sodium/potassium- transporting ATPase subunit alpha-3 Sodium/potassium- transporting ATPase subunit alpha-4 Sodium/potassium- transporting ATPase subunit beta-1 Sodium/potassium- transporting ATPase subunit beta-2 Sodium/potassium- transporting ATPase subunit beta-3 ATPase, (Na+)/K+ transporting, beta 4 polypeptide Sodium/potassium- transporting ATPase subunit gamma Chloride channel protein ClC-Ka Potassium- transporting ATPase subunit beta Potassium- transporting ATPase alpha chain 1 Transient receptor potential cation channel subfamily V member 5 Sodium/calcium exchanger 1 Aquaporin-2 Aquaporin-3 Aldosterone Cl- Cl- Na+ Cl- H+ H+ K+ Ca+ Ca+ Ca+ Na+ Na+ H2O H2O H2O Na+ Cl- Ca+ Angiotensin I Angiotensin II Vasopressin Lumen Interstitium Blood Vessel Distal Convoluted Tubule Posterior Pituitary Gland Vasopressin is released from the posterior pituitary gland into the circulation and reaches the kidneys. Its action on the distal convoluted tubule causes an increase in water permeability and subsequent water reabsorption by the body. Aldosterone is released from the adrenal cortex and acts on the distal convoluted tubule to make it more permeable to sodium to allow for sodium reuptake by the body.
Sodium Sodium Potassium Potassium REN SLC12A3 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 Unknown FXYD2 CLCNKA ATP4B ATP4A TRPV5 SLC8A1 AQP2 AQP3 Aldosterone Chloride ion Chloride ion Sodium Chloride ion Hydrogen Ion Hydrogen Ion Potassium Calcium Calcium Calcium Sodium Sodium Water Water Water Sodium Chloride ion Calcium Angiotensin I Angiotensin II Vasopressin
Na+ Na+ K+ K+ REN SLC12A3 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 FXYD2 CLCNKA ATP4B ATP4A TRPV5 SLC8A1 AQP2 AQP3 Aldostr Cl- Cl- Na+ Cl- H+ H+ K+ Ca+ Ca+ Ca+ Na+ Na+ H2O H2O H2O Na+ Cl- Ca+ Angio1 Ang II ADH Lumen Interstitium Blood Vessel Distal Convoluted Tubule Posterior Pituitary Gland Vasopressin is released from the posterior pituitary gland into the circulation and reaches the kidneys. Its action on the distal convoluted tubule causes an increase in water permeability and subsequent water reabsorption by the body. Aldosterone is released from the adrenal cortex and acts on the distal convoluted tubule to make it more permeable to sodium to allow for sodium reuptake by the body.
Na+ Na+ K+ K+ REN SLC12A3 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 FXYD2 CLCNKA ATP4B ATP4A TRPV5 SLC8A1 AQP2 AQP3 Aldostr Cl Cl Na+ Cl H+ H+ K+ Ca2+ Ca2+ Ca2+ Na+ Na+ H2O H2O H2O Na+ Cl Ca2+ Angio1 Ang II ADH