Na+
Na+
K+
K+
REN
SLC12A3
ATP1A1
ATP1A2
ATP1A3
ATP1A4
ATP1B1
ATP1B2
ATP1B3
FXYD2
CLCNKA
ATP4B
ATP4A
TRPV5
SLC8A1
AQP2
AQP3
Aldostr
Cl-
Cl-
Na+
Cl-
H+
H+
K+
Ca+
Ca+
Ca+
Na+
Na+
H2O
H2O
H2O
Na+
Cl-
Ca+
Angio1
Ang II
ADH
Lumen
Interstitium
Blood Vessel
Distal Convoluted Tubule
Posterior Pituitary Gland
Vasopressin is released from
the posterior pituitary
gland into the circulation
and reaches the kidneys. Its
action on the distal
convoluted tubule causes an
increase in water
permeability and subsequent
water reabsorption by the
body.
Aldosterone is released from
the adrenal cortex and acts
on the distal convoluted
tubule to make it more
permeable to sodium to allow
for sodium reuptake by the
body.