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Squalene monooxygenase Solute carrier organic anion transporter family member 1B1 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 3 Solute carrier family 22 member 5 Cytochrome P450 1A2 Cytochrome P450 2C19 Cytochrome P450 3A4 Cytochrome P450 2C9 Cytochrome P450 1A2 Squalene synthase Cytochrome P450 1A2 Cytochrome P450 2C19 Cytochrome P450 3A4 Cytochrome P450 1A2 Cytochrome P450 2C8 Cytochrome P450 1A2 Cytochrome P450 2B6 Cytochrome P450 2C9 Cytochrome P450 1A2 Terbinafine (S)-2,3-Epoxysqualene Cholesterol N-Desmethylhydroxyterbinafine Carboxyterbinafine N-Desmethylterbinafine dihydrodiol derivative (2) N-Desmethylterbinafine dihydrodiol derivative (1) 1-Naphthoic acid 1-Naphthalenemethanol Terbinafine Terbinafine Terbinafine N-Desmethylterbinafine dihydrodiol derivative (1) Carboxyterbinafine N-Desmethylhydroxyterbinafine N-Desmethylterbinafine dihydrodiol derivative (1) N-Desmethylhydroxyterbinafine N-Desmethylterbinafine dihydrodiol derivative (2) N-Desmethylterbinafine dihydrodiol derivative (2) 1-Naphthalenemethanol 1-Naphthoic acid N-Desmethylterbinafine 1-Naphthaldehyde Hydroxyterbinafine Terbinafine dihydrodiol derivative (1) Terbinafine dihydrodiol derivative (2) Squalene O2 NADPH H2O NADP Farnesyl pyrophosphate H+ NADPH PPi NADP O2 O2 NADPH H2O NADP H+ NADPH NADP NADPH O2 H+ NADP H2O O2 H+ H2O NADPH O2 NADP NADPH O2 NADP NADPH