Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
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ATP-dependent translocase ABCB1 ATP-dependent translocase ABCB1 ATP-dependent translocase ABCB1 ATP-dependent translocase ABCB1 Cytochrome P450 1A2 Cytochrome P450 3A4 Cytochrome P450 1A2 Cytochrome P450 1A2 Hydroxynorfentanyl Norfentanyl Despropionylfentanyl Fentanyl Fentanyl Hydroxynorfentanyl Norfentanyl Despropionylfentanyl O2 NADPH Hydroxyfentanyl NADP H+ H2O NADPH NADP NADPH NADP NADPH NADP Heme Heme Heme Heme Excretion Metabolites excreted mainly renally through the kidneys. <7% as Fentanyl. 9% is excreted in the feces. Hepatocyte Endoplasmic Retiuclum 99% of fentanyl is metabolized into Norfentanyl Fentanyl is injected intravenously or intramuscularly Fentanyl is 80-85% bound to plasma proteins. Bile ducts
Endoplasmic Reticulum ABCB1 ABCB1 ABCB1 ABCB1 CYP1A2 CYP3A4 CYP1A2 CYP1A2 Hydroxynorfentanyl Norfentanyl Despropionylfentanyl Fentanyl Fentanyl Hydroxynorfentanyl Norfentanyl Despropionylfentanyl Oxygen NADPH Hydroxyfentanyl NADP Hydrogen Ion Water NADPH NADP NADPH NADP NADPH NADP Excretion