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Showing 49731 - 49740 of 605359 pathways
SMPDB ID Pathway Name and Description Pathway Class Chemical Compounds Proteins

SMP0145265

Pw146933 View Pathway

Ferric derisomaltose Drug Metabolism Action Pathway

Drug Action
  • Ferric derisomaltose

SMP0145272

Pw146940 View Pathway

Zinc phenolsulfonate Drug Metabolism Action Pathway

Drug Action
  • Zinc phenolsulfonate

SMP0145258

Pw146926 View Pathway

Magnesium malate Drug Metabolism Action Pathway

Drug Action
  • Magnesium malate

SMP0145270

Pw146938 View Pathway

Cedazuridine Drug Metabolism Action Pathway

Drug Action
  • Cedazuridine

SMP0145433

Pw147102 View Pathway

Zuclopenthixol H1 Antihistamine Neurological Sleep Action Pathway

Zuclopenthixol is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. Wakefulness is regulated by histamine in the tuberomammillary nucleus, a part of the hypothalamus. Histidine is decarboxylated into histamine in the neuron. Histamine is transported into synaptic vesicles by a monoamine transporter then released into the synapse. Normally histamine would activate the H1 histamine receptor on the post-synaptic neuron in the tuberomammillary nucleus. Zuclopenthixol inhibits the H1 histamine receptor, preventing the depolarization of the post-synaptic neuron. This prevents the wakefulness signal from being sent to the major areas of the brain, causing sleepiness.
Drug Action

SMP0145430

Pw147099 View Pathway

Trazodone H1 Antihistamine Neurological Sleep Action Pathway

Trazodone is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. Wakefulness is regulated by histamine in the tuberomammillary nucleus, a part of the hypothalamus. Histidine is decarboxylated into histamine in the neuron. Histamine is transported into synaptic vesicles by a monoamine transporter then released into the synapse. Normally histamine would activate the H1 histamine receptor on the post-synaptic neuron in the tuberomammillary nucleus. Trazodone inhibits the H1 histamine receptor, preventing the depolarization of the post-synaptic neuron. This prevents the wakefulness signal from being sent to the major areas of the brain, causing sleepiness.
Drug Action

SMP0145425

Pw147094 View Pathway

Propiomazine H1 Antihistamine Neurological Sleep Action Pathway

Propiomazine is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. Wakefulness is regulated by histamine in the tuberomammillary nucleus, a part of the hypothalamus. Histidine is decarboxylated into histamine in the neuron. Histamine is transported into synaptic vesicles by a monoamine transporter then released into the synapse. Normally histamine would activate the H1 histamine receptor on the post-synaptic neuron in the tuberomammillary nucleus. Propiomazine inhibits the H1 histamine receptor, preventing the depolarization of the post-synaptic neuron. This prevents the wakefulness signal from being sent to the major areas of the brain, causing sleepiness.
Drug Action

SMP0145438

Pw147107 View Pathway

Pamidronate Drug Metabolism Pathway

Gadoversetamide is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Gadoversetamide passes through the liver and is then excreted from the body mainly through the kidney.
Metabolic

SMP0145445

Pw147114 View Pathway

Risedronate Drug Metabolism Pathway

Gadoversetamide is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Gadoversetamide passes through the liver and is then excreted from the body mainly through the kidney.
Metabolic

SMP0144941

Pw146609 View Pathway

Mandelic acid Drug Metabolism Action Pathway

Drug Action
Showing 49731 - 49740 of 65006 pathways