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Showing 161 - 180 of 1576 proteins

Protein ID

Protein

Pathways

Q9C0C7

View in UniProt

Activating molecule in BECN1-regulated autophagy protein 1

Gene Name: AMBRA1

Q9H6R3

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HMDBP11602

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Acyl-CoA synthetase short-chain family member 3, mitochondrial

Gene Name: ACSS3

Activates acetate so that it can be used for lipid synthesis or for energy generation (By similarity).

Q58HT5

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HMDBP07278

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Acyl-CoA wax alcohol acyltransferase 1

Gene Name: AWAT1

Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has a preference for arachidyl alcohol as well as decyl alcohol, demonstrating its relatively poor activity using saturated long chain alcohols (C16, C18, and C20).

Q08AH1

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HMDBP04188

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Acyl-coenzyme A synthetase ACSM1, mitochondrial

Gene Name: ACSM1

Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4-unsaturated acids (in vitro). Functions as GTP-dependent lipoate-activating enzyme that generates the substrate for lipoyltransferase (By similarity).

Q68CK6

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HMDBP08700

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Acyl-coenzyme A synthetase ACSM2B, mitochondrial

Gene Name: ACSM2B

Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4-unsaturated acids (in vitro).

Q8WYK0

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HMDBP00024

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Acyl-coenzyme A thioesterase 12

Gene Name: ACOT12

Hydrolyzes acetyl-CoA to acetate and CoA.

O75608

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HMDBP00056

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Acyl-protein thioesterase 1

Gene Name: LYPLA1

Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity and also low lysophospholipase activity.

P07311

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HMDBP00553

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Acylphosphatase-1

Gene Name: ACYP1

Its physiological role is not yet clear.

P46108

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Adapter molecule crk

Gene Name: CRK

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

P07741

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HMDBP00438

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Adenine phosphoribosyltransferase

Gene Name: APRT

Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.

P00813

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HMDBP00664

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Adenosine deaminase

Gene Name: ADA

Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.

P55263

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HMDBP00640

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Adenosine kinase

Gene Name: ADK

ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.

P29274

View in UniProt

HMDBP01652

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Adenosine receptor A2a

Gene Name: ADORA2A

Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase

P29275

View in UniProt

HMDBP01656

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Adenosine receptor A2b

Gene Name: ADORA2B

Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase

P23526

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HMDBP00662

View in HMDB

Adenosylhomocysteinase

Gene Name: AHCY

Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.

Q08828

View in UniProt

HMDBP00711

View in HMDB

Adenylate cyclase type 1

Gene Name: ADCY1

This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning.

Q96PN6

View in UniProt

HMDBP04127

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Adenylate cyclase type 10

Gene Name: ADCY10

Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation.

Q08462

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HMDBP00921

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Adenylate cyclase type 2

Gene Name: ADCY2

This is a membrane-bound, calmodulin-insensitive adenylyl cyclase.

P54819

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HMDBP04072

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Adenylate kinase 2, mitochondrial

Gene Name: AK2

Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. This small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth. Plays a key role in hematopoiesis.

P00568

View in UniProt

HMDBP00562

View in HMDB

Adenylate kinase isoenzyme 1

Gene Name: AK1

Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth.
Showing 161 - 180 of 1576 proteins