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Matched Description: enzyme results in accumulation of ammmonia and reticulocytes in blood; glutamine in plasma, carnitine … and ferritin in serum, and arginine, lysine and ornithine in urine. Symptoms include bone marrow … abnormality, growth retardation, hyperammoniemia, mental retardation, pancreatitis, and seizures.

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: -isoleucine, L-leucine, L-phenylalanine, L-serine, L-threonine, L-tryptophan, L-valine, and L-tyrosine in … urine. Symptoms include pellagra, psychosis, ataxia, and mental retardation. Treatment includes nicotinamide.

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: responsible for approximately 90% of the kidney's reabsorption of glucose, and can be found in the S1 … kidney. There are some drugs that inhibit SGLT2 and are used to decrease blood sugar in patients with type 2 diabetes mellitus.

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: Etacrynic acid (also known as ethacrynic acid and Edecrin) is a loop diuretic that can inhibit … water reabsorption by binding and inhibiting solute carrier family 12 member 1 (also known as sodium … environment in lumen than interstitium, and result in prevention of water reabsorption due to diminished osmotic gradient in nephron.

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: transports chloride and sodium from lumen to epithelial cell, and sodium/potassium ATPases facilitate

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: treat hypertension and decompensated heart failure. Indapamide can inhibit sodium-chloride symporter … member 3) can translocate chloride and sodium from lumen to epithelial cell. Sodium-potassium ATPase

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: chloride and sodium from lumen to epithelial cell, and sodium/potassium ATPases facilitate the export of

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: used to manage hypertension and edema. It acts by blocking epithelial sodium channels in the late … in the nephron. This primarily contributes to an increase in sodium excretion and consequentially … , fluid excretion which decreases blood volume and blood pressure. Potassium secretion is indirectly … action for potassium-sparing drugs -- and has the potential to induce hyperkalemia which can potentially lead to severe heart arrhythmias.

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 2 … Solute carrier family 22 member 6 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: chloride and sodium from lumen to epithelial cell, and sodium/potassium ATPases facilitate the

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: called thiazides. Thiazides and thiazide-like drugs are diuretics commonly employed to control … hypertension. Trichloromethiazide acts by inhibiting chloride and potentially sodium reabsorption in the … increased fluid loss which ultimately reduces blood volume and pressure. Trichlormethiazide also acts … to inhibit sodium uptake and increase potassium excretion which also serves to increase fluid loss … . The long-term antihypertensive effects of thiazides and thiazide-like drugs such as

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)