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Matched Description: acid transporter which facilitates the reuptake of glycine, proline, and hydroxyproline. This … disorder is characterized by a large accumulation of glycine, proline, and hydroxyproline in the urine … . Symptoms of the disorder include urolithiasis and mental retardation.

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: chloride and sodium from lumen to epithelial cell, and sodium/potassium ATPases facilitate the export of

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: in the kidneys. The mutations cause this process to be compromised and allows the amino acids to … build up and have a high concentration in urine. This causes crystals to form and become stones as they … , develop infection and disrupt the passing of urine through the urinary tract if the stones create a blockage there.

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: Furosemide (also named Lasix) is a medication that can be used for high blood pressure and fluid … build-up which caused by heart failure, liver scarring, or kidney disease. Furosemide can bind and … from lumen to basolateral interstitium, which lead to more hypertonic in lumen and less hypertonic in

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: that count for 5% of total amount. Solute carrier family 12 member 3 transports chloride and sodium … from lumen to epithelial cell, and sodium/potassium ATPases facilitate the export of sodium to

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: chloride and sodium from lumen to epithelial cell, and sodium/potassium ATPases facilitate the export

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: hypertonic and a decreased osmotic gradient thereby reducing the water reabsorption. In the nephron, the … think ascending limb reabsorbs 25% of sodium and is a good target for diuretics.

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: Amiloride is a diuretic that inhibits the sodium channels in the late distal convoluted tubule and … reabsorption results in increased osmolarity in the lumen and decreased osmolarity in the interstitium … electrochemical gradient and therefore, inhibits potassium excretion. Amiloride causes an increase in … sodium excretion and a decrease in potassium secretion. The drug is typically prescribed to patients with depleted potassium.

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 2 … Solute carrier family 22 member 6 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: molecule that belongs to a class of drugs called thiazides. Thiazides and thiazide-like drugs are diuretics … the nephron and therefore increase fluid loss which decreases extracellular fluid (ECF), plasma … volume, and ultimately blood pressure. In the case of quinethazone, it inhibits the sodium-chloride … long-term mechanism of action isn’t as well-characterized and it is thought that other processes … beyond regulating plasma and ECF volumes are involved as these two volumes return to baseline within 4-6 weeks of first use of thiazides.

Matched Compounds: Aldosterone

Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

Matched Description: , and due to the enzyme not being entirely functional, it builds up in the cell, while aldosterone … less severe changes in aldosterone and 18-OHB concentrations. The CMO-II deficiency, and its … levels of aldosterone being lower due to this deficiency, excess sodium is excreted in the urine, and … aldosterone deficiency II among other names, is a genetic disorder that is autosomally linked. It is … formation of aldosterone from 18-hydroxycorticosterone (18-OHB), as well as converting progesterone to

Matched Compounds: Aldosterone

Matched Protein Synonyms: Aldosterone synthase … Aldosterone-synthesizing enzyme … Aldosterone synthase … Aldosterone-synthesizing enzyme … Hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 2, isoform CRA_a

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone … 17-oh progesterone