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Matched Description: , deoxycorticosterone, aldosterone and cortisol. Symptoms include salt-wasting crises in infancy due … to the lack of aldosterone, like spitting, poor weight gain, vomiting, severe dehydration, and … to aldosterone. A defect in this enzyme results in accumulation of 17-Hydroxyprogesterone … , progesterone and 17a-Hydroxypregnenolone, androstenedione, and testosterone; decreased levels of cortexolone … circulatory collapse. The high level of testosterone results in virilization and genital ambiguity of female infants.

Matched Compounds: Aldosterone

Matched Protein Synonyms: Aldosterone synthase … Aldosterone-synthesizing enzyme … Aldosterone synthase … Aldosterone-synthesizing enzyme … Hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 2, isoform CRA_a

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone … 17-oh progesterone

Matched Description: aldosterone deficiency among other names, is a genetic disorder that is autosomally linked and … , also called aldosterone synthase, which is used to catalyze the conversion of 18-hydroxycorticosterone … to aldosterone. This leads to a decrease in the amount of aldosterone present in the cells, which is … deficiency, aldosterone levels are so low that they are undetectable in plasma.

Matched Compounds: Aldosterone

Matched Protein Synonyms: Aldosterone synthase … Aldosterone-synthesizing enzyme … Aldosterone synthase … Aldosterone-synthesizing enzyme … Hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 2, isoform CRA_a

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone … 17-oh progesterone

Matched Description: recessive disorder and caused by a defective 11-beta-hydroxylase. 11-beta-hydroxylase catalyzes the … conversion of cortexolone into cortisol which is useful for maintaining blood sugar levels and … endoplasmic reticulum (ER). Symptoms of the disorder include abnormality of hair growth rate and

Matched Compounds: Aldosterone

Matched Protein Synonyms: Aldosterone synthase … Aldosterone-synthesizing enzyme … Aldosterone synthase … Aldosterone-synthesizing enzyme … Hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 2, isoform CRA_a

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone … 17-oh progesterone

Matched Description: metabolism (IEM) and autosomal recessive disorder of the steroidogenesis pathway. It is caused by an defect … produced, cortisol levels in the cell are lowered, and as cortisol is used in the production of other … of cortisol produced in the adrenal glands. Symptoms include abnormal genitalia for both males and

Matched Compounds: Aldosterone

Matched Protein Synonyms: Aldosterone synthase … Aldosterone-synthesizing enzyme … Aldosterone synthase … Aldosterone-synthesizing enzyme … Hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 2, isoform CRA_a

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone … 17-oh progesterone

Matched Description: metabolism (IEM) and autosomal recessive disorder of the steroidogenesis pathway. It is caused by an defect … produced, cortisol levels in the cell are lowered, and as cortisol is used in the production of other … of cortisol produced in the adrenal glands. Symptoms include abnormal genitalia for both males and

Matched Compounds: Aldosterone

Matched Protein Synonyms: Aldosterone synthase … Aldosterone-synthesizing enzyme … Aldosterone synthase … Aldosterone-synthesizing enzyme … Hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 2, isoform CRA_a

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone … 17-oh progesterone

Matched Description: Carbimazole an imidazole antithyroid agent used for the treatment of hyperthyroidism and … enters the thyroid gland and is transported into thyroid follicle cells, where it inhibits the … production of the thyroid hormones T3 (liothyronine) and T4 (thyroxine). Thyroid hormone synthesis begins … -iodinated tyrosine (MIT) and di-iodinated tyrosine (DIT). The thyroglobulin molecules enter the follicle … lumen for this reaction via exocytosis. Coupling of MIT and DIT occurs, again using TPO. Coupling

Matched Protein Synonyms: Neutrophil cytochrome b 22 kDa polypeptide … Neutrophil cytochrome b 22 kDa polypeptide … Neutrophil cytochrome b 22 kDa polypeptide … Neutrophil cytochrome b 22 kDa polypeptide … Neutrophil cytochrome b 22 kDa polypeptide

Matched Compound Synonyms: [oh(oh)] … [oh(oh)] … [oh(oh)]

Matched Description: metabolism, temperature regulation and growth/development. Thyroid hormone synthesis begins in the … nucleus of a thyroid follicular cell, as thyroglobulin synthesis occurs here and is transported to the … space, and then transported through exocytosis to the follicle colloid. There, thyroglobulin is … joined by iodide that has been transported from the blood, through the thyroid follicular cell and … arrived in the the follicle colloid using pendrin, and hydrogen peroxide to be catalyzed by thyroid

Matched Protein Synonyms: Neutrophil cytochrome b 22 kDa polypeptide … Neutrophil cytochrome b 22 kDa polypeptide … Neutrophil cytochrome b 22 kDa polypeptide … Neutrophil cytochrome b 22 kDa polypeptide

Matched Compound Synonyms: [oh(oh)] … [oh(oh)] … [oh(oh)] … [oh(oh)]

Matched Description: Acemetacin is highly metabolized and degraded by esterolytic cleavage to form its major and active … symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a … approved. It has analgesic, antipyretic, and anti-inflammatory effects. It targets the prostaglandin G … /H synthase-1 (COX-1) and prostaglandin G/H synthase-2 (COX-2) in the cyclooxygenase pathway. The … inducible enzyme, and during inflammation, it is responsible for prostaglandin synthesis. It leads to

Matched Proteins: Solute carrier family 22 member 6

Matched Compound Synonyms: for oral administration. acemetacin mode of action as an anti-inflammatory and antirheumatic agent may … be due to inhibition of synthesis and release of prostaglandins. the usefulness of indometacin, the … . acemetacin is highly metabolized and degraded by esterolytic cleavage to form its major and active … , n-desacylation and part of them are also transformed by conjugation with glucuronic acid. the … blood flow and glomerular filtration thus, acemetacin causes a decreased renal function, transient

Matched Description: Spironolactone is a steroidal, non specific, orally administered aldosterone antagonist used mainly … , hypertension, adrenal hyperplasia, edema, and nephrotic syndrome. It has also been shown to decrease … proteinuria. Spironolactone can be found under the brand names Aldactazide, Aldactone, and Carospir … sodium (Na+) and water (H2O) excretion and potassium (K+) retention. Once spironolactone is bound to the … MR, it blocks aldosterone from binding which inhibits aldosterone dependent sodium potassium

Matched Compounds: Aldosterone

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone … (+)-aldosterone

Matched Description: Aldosterone is a hormone produced in the zona glomerulosa of the adrenal cortex. It's function is … to act on the distal convoluted tubule and the collecting duct of the nephron to make them more … membrane, activating the G protein and triggering a signaling cascade. The end result is the activation of … mitochondria. From there, cholesterol undergoes a series of reactions in both the mitochondrion and the … smooth endoplasmic reticulum (steroidogenesis) where it finally becomes aldosterone.

Matched Compounds: Aldosterone

Matched Protein Synonyms: Aldosterone synthase … Aldosterone-synthesizing enzyme … Aldosterone synthase … Aldosterone-synthesizing enzyme … Aldosterone synthase

Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone … (+)-aldosterone