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Search for '28cortisol oh aldosterone 22 and subject 3ametabolic' in 'all pathways' in 'Homo sapiens' returned 59240 results

SMP0000134

Pw000343 View Pathway
Drug Action

Spironolactone Action Pathway

  • Matched Description: receptor inside the principal cells of the late distal tubule and collecting tubule. Aldosterone … Spironolactone is a potassium-sparing diuretic. It acts by competing with aldosterone for its … increases sodium reabsorption and potassium excretion by up-regulating the expression of basolateral sodium … -potassium ATPases as well as luminal (apical) sodium and potassium channels. Sodium in the nephron … hyperosmotic and establishes an osmotic gradient, facilitating water reabsorption through aquaporin

  • Matched Compounds: Aldosterone

  • Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    SMP0000371

    Pw000178 View Pathway
    Disease

    Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH

  • Matched Description: Congenital Lipoid Adrenal Hyperplasia (CLA),also called steroid 20-22 desmolase deficiency and … lipoid CAH, is an autosomal recessive disorder and caused by a defective cholesterol side-chain cleavage … disorder is not clear. Extra glucocorticoid and mineral replacement could be the potential treatments.

  • Matched Compounds: Aldosterone

  • Matched Protein Synonyms: Aldosterone synthase … Aldosterone-synthesizing enzyme … Aldosterone synthase … Aldosterone-synthesizing enzyme … Hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 2, isoform CRA_a

  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone … 17-oh progesterone

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    SMP0000135

    Pw000344 View Pathway
    Drug Action

    Eplerenone Action Pathway (Old)

  • Matched Description: inside the principal cells of the late distal tubule and collecting tubule. Aldosterone increases … Eplerenone is a potassium-sparing diuretic. It acts by competing with aldosterone for its receptor … sodium reabsorption and potassium excretion by up-regulating the expression of basolateral sodium … -potassium ATPases as well as luminal (apical) sodium and potassium channels. Sodium in the nephron lumen … hyperosmotic and establishes an osmotic gradient, facilitating water reabsorption through aquaporin channels

  • Matched Compounds: Aldosterone

  • Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    SMP0125798

    Pw127365 View Pathway
    Disease

    Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH

  • Matched Description: Congenital Lipoid Adrenal Hyperplasia (CLA),also called steroid 20-22 desmolase deficiency and … lipoid CAH, is an autosomal recessive disorder and caused by a defective cholesterol side-chain cleavage … disorder is not clear. Extra glucocorticoid and mineral replacement could be the potential treatments.

  • Matched Compounds: Aldosterone

  • Matched Protein Synonyms: Aldosterone synthase … Aldosterone-synthesizing enzyme … Aldosterone synthase … Aldosterone-synthesizing enzyme … Hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 2, isoform CRA_a

  • Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone … 17-oh progesterone

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    SMP0000585

    Pw000561 View Pathway
    Disease

    Lysinuric Protein Intolerance (LPI)

  • Matched Description: of metabolism (IEM) and autosomal recessive disorder of the kidney function pathway. It is caused … involved in the uptake of amino acids, both with sodium for neutral amino acids, and without for … dibasic amino acids. In this disorder, the amino acids lysin, arginine and ornithine, found in protein … urea cycle. LPI is characterized by a shortage of lysine, arginine and ornithine within the body … after weaning, nausea and vomiting following a meal containing large amounts of protein, as well as

  • Matched Compounds: Aldosterone

  • Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    SMP0000080

    Pw000326 View Pathway
    Drug Action

    Polythiazide Action Pathway

  • Matched Description: reabsorption that count for 5% of total amount. Solute carrier family 12 member 3 transports chloride and … sodium from lumen to epithelial cell, and sodium/potassium ATPases facilitate the export of sodium

  • Matched Compounds: Aldosterone

  • Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    SMP0000122

    Pw000340 View Pathway
    Drug Action

    Chlorthalidone Action Pathway

  • Matched Description: transports chloride and sodium from lumen to epithelial cell, and sodium/potassium ATPases facilitate the

  • Matched Compounds: Aldosterone

  • Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    SMP0000103

    Pw000333 View Pathway
    Drug Action

    Cyclothiazide Action Pathway

  • Matched Description: and sodium from lumen to epithelial cell, and sodium/potassium ATPases facilitate the export of

  • Matched Compounds: Aldosterone

  • Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    SMP0000118

    Pw000338 View Pathway
    Drug Action

    Torsemide Action Pathway

  • Matched Description: the drug class of loop diuretics. It is commonly used to manage hypertension and edema in cases of … reduces the uptake of water and serves to both increase water loss and reduce blood pressure

  • Matched Compounds: Aldosterone

  • Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    SMP0000583

    Pw000559 View Pathway
    Disease

    Blue Diaper Syndrome

  • Matched Description: symptoms can include bacterial infections, damage to various parts of the eye, hypercalcemia, and impaired … hypercalcemia, and a tryptophan restricted diet to prevent all systems. If bacterial infections are common, antibiotics may be prescribed.

  • Matched Compounds: Aldosterone

  • Matched Proteins: Solute carrier family 22 member 6 … Solute carrier family 22 member 2 … Sodium- and chloride-dependent transporter XTRP3 … Neutral and basic amino acid transport protein rBAT

  • Matched Protein Synonyms: Neuronal and epithelial glutamate transporter … Water channel protein for red blood cells and kidney proximal tubule … Water channel protein for red blood cells and kidney proximal tubule

  • Matched Compound Synonyms: [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-) … [co2(oh)](-)

    • BioPAX SVG SBGN SBML PWML All files (.zip)