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CDP-
diacylglycerol-
-inositol 3-
phosphatidyltransferase
Synaptojanin-1
Phosphatidylinositol-
4,5- bisphosphate
3-kinase
catalytic subunit
alpha isoform
Phosphatidylinositol
3-kinase
regulatory
subunit alpha
Phosphatidylinositol
3-kinase
catalytic subunit
type 3
Phosphoinositide
3-kinase
regulatory
subunit 4
Beclin-1
Activating
molecule in
BECN1-regulated
autophagy protein
1
1-
phosphatidylinositol-
3-phosphate
5-kinase
Polyphosphoinositide
phosphatase
Protein VAC14
homolog
Phosphatidylinositol
4-phosphate
5-kinase type-1
alpha
Phosphatidylinositol
4-phosphate
5-kinase type-1
alpha
Synaptojanin-1
Type II inositol
3,4-bisphosphate
4-phosphatase
Phosphatidylinositol-
5-phosphate
4-kinase type-2
alpha
Phosphatidylinositol
3,4,5-
trisphosphate
5-phosphatase 1
Phosphatidylinositol
4-phosphate
5-kinase type-1
alpha
72 kDa inositol
polyphosphate
5-phosphatase
Synaptojanin-1
Synaptojanin-1
Phosphatidylinositol
4-kinase alpha
Phosphatidylinositol
4-phosphate
3-kinase C2
domain-containing
subunit alpha
Phosphatidylinositol
4,5-bisphosphate
3-kinase
catalytic subunit
alpha isoform
Phosphatidylinositol
3,4,5-
trisphosphate
3-phosphatase and
dual-specificity
protein
phosphatase PTEN
Phosphatidylinositol
4,5-bisphosphate
3-kinase
catalytic subunit
alpha isoform
1-
phosphatidylinositol
4,5-bisphosphate
phosphodiesterase
beta-1
Phosphatidylinositol
4-phosphate
5-kinase type-1
alpha
Phosphatidylinositol
3,4,5-
trisphosphate
5-phosphatase 1
72 kDa inositol
polyphosphate
5-phosphatase
Synaptojanin-1
Phosphatidylinositol
3,4,5-
trisphosphate
5-phosphatase 1
Phosphatidylinositol-
5-phosphate
4-kinase type-2
alpha
Synaptojanin-1
Polyphosphoinositide
phosphatase
Phosphatidylinositol
4-phosphate
5-kinase type-1
alpha
myo-Inositol
Inositol 1,4,5-
trisphosphate
CDP-
DG(16:0/18:1(9Z))
PI(16:0/18:1(9Z))
Cytidine
monophosphate
PIP(18:1(9Z)/16:0)
H
2
O
P
i
ATP
ADP
ATP
ADP
ATP
PIP2(16:0/18:1(9Z))
ADP
ATP
ADP
ATP
PIP2(16:0/18:1(9Z))
ADP
H
2
O
P
i
H
2
O
P
i
ATP
ADP
PIP3(16:0/18:1(9Z))
H
2
O
P
i
ATP
ADP
H
2
O
P
i
H
2
O
P
i
PIP[4'](16:0/18:1(9Z))
H
2
O
P
i
ATP
ADP
ATP
ADP
ATP
ADP
H
2
O
PIP2[4,5](16:0/18:1(9Z))
P
i
ATP
ADP
H
2
O
DG(16:0/18:1(9Z)/0:0)
ATP
ADP
H
2
O
P
i
H
2
O
P
i
H
2
O
P
i
H
2
O
PIP[5'](16:0/18:1(9Z))
P
i
ATP
ADP
H
2
O
P
i
ATP
ADP
ATP
ADP
Magnesium
Manganese
Manganese
Calcium
Magnesium
Calcium
Inositol
Phosphate
Metabolism
Inositol
Phosphate
Metabolism
CDIPT
SYNJ1
PIK3CA
PIK3R1
PIK3C3
PIK3R4
Unknown
AMBRA1
PIKFYVE
FIG4
VAC14
PIP5K1A
PIP5K1A
SYNJ1
INPP4B
PIP4K2A
INPP5D
PIP5K1A
INPP5E
SYNJ1
SYNJ1
PI4KA
PIK3C2A
ERBB2
Unknown
PIK3CD
PIK3R1
PTEN
PIK3CD
PIK3R1
PLCB1
PIP5K1A
INPP5D
INPP5E
SYNJ1
INPP5D
PIP4K2A
SYNJ1
FIG4
VAC14
PIKFYVE
PIP5K1A
myo-Inositol
Inositol 1,4,5-
trisphosphate
CDP-
DG(16:0/18:1(9Z))
PI(16:0/18:1(9Z))
Cytidine
monophosphate
PIP(18:1(9Z)/16:0)
Water
Phosphate
Adenosine
triphosphate
Adenosine
diphosphate
Adenosine
triphosphate
Adenosine
diphosphate
Adenosine
triphosphate
PIP2(16:0/18:1(9Z))
Adenosine
diphosphate
Adenosine
triphosphate
Adenosine
diphosphate
Adenosine
triphosphate
PIP2(16:0/18:1(9Z))
Adenosine
diphosphate
Water
Phosphate
Water
Phosphate
Adenosine
triphosphate
Adenosine
diphosphate
PIP3(16:0/18:1(9Z))
Water
Phosphate
Adenosine
triphosphate
Adenosine
diphosphate
Water
Phosphate
Water
Phosphate
PIP[4'](16:0/18:1(9Z))
Water
Phosphate
Adenosine
triphosphate
Adenosine
diphosphate
Adenosine
triphosphate
Adenosine
diphosphate
Adenosine
triphosphate
Adenosine
diphosphate
Water
PIP2[4,5](16:0/18:1(9Z))
Phosphate
Adenosine
triphosphate
Adenosine
diphosphate
Water
DG(16:0/18:1(9Z)/0:0)
Adenosine
triphosphate
Adenosine
diphosphate
Water
Phosphate
Water
Phosphate
Water
Phosphate
Water
PIP[5'](16:0/18:1(9Z))
Phosphate
Adenosine
triphosphate
Adenosine
diphosphate
Water
Phosphate
Adenosine
triphosphate
Adenosine
diphosphate
Adenosine
triphosphate
Adenosine
diphosphate
Inositol
Phosphate
Metabolism
Inositol
Phosphate
Metabolism