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AcrEF-TolC
multidrug
efflux
transport
system-membrane
fusion protein
Unknown
Unknown
Low affinity
tryptophan
permease
UDP-
glucuronosyltransferase
1-6
Tryptophanase
Indoxyl glucuronide
indole
indole
indole
indole
indole
L-Tryptophan
L-Tryptophan
Indoxyl glucuronide
L-Tryptophan
L-Tryptophan
H
2
O
NH
3
pyruvate
Reduces
Erythropoetin
production
resulting in
renal anemia