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Adenine
intestinal
membrane
transporter
Adenine
membrane
transporter
Guanine
intestinal
membrane
transporter
Guanine
membrane
transporter
Solute carrier
family 23
member 1
Purine
nucleoside
phosphorylase
Adenosine
deaminase
Purine
nucleoside
phosphorylase
Xanthine
dehydrogenase/oxidase
Guanine
deaminase
Xanthine
Adenine
Adenine
Adenine
Guanine
Guanine
Guanine
Guanine
Xanthine
Adenosine
P
i
Ribose 1-phosphate
H
2
O
Inosine
NH
3
P
i
Hypoxanthine
Ribose 1-phosphate
O
2
H
2
O
H
2
O
2
H
2
O
NH
3
Zinc (II) ion
FAD
2Fe-2S
Molybdopterin
Zinc (II) ion
Adenine
Renal failure
Endothelial
dysfunction
Hepatocyte
Intestinal Lumen
Intestinal epithelial cell
Intestinal epithelial cell
Adenine and guanine are
obtained from red meats
Cytosol
Unknown
Unknown
Unknown
Unknown
SLC23A1
PNP
ADA
PNP
XDH
GDA
Xanthine
Adenine
Adenine
Adenine
Guanine
Guanine
Guanine
Guanine
Xanthine
Adenosine
Phosphate
Ribose
1-phosphate
Water
Inosine
Ammonia
Phosphate
Hypoxanthine
Ribose
1-phosphate
Oxygen
Water
Hydrogen
peroxide
Water
Ammonia
Adenine
Renal failure
Endothelial
dysfunction