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Pathway Description
Physostigmine Action Pathway (new)
Homo sapiens
Drug Action Pathway
Created: 2023-08-03
Last Updated: 2023-11-27
Physostigmine is a cholinesterase inhibitor used to treat glaucoma, once administered it is rapidly absorbed and can travel across membranes even the blood-brain barrier. Physostigmine acts on the acetylcholinesterase enzyme and inhibits it so it cannot break down acetylcholine. By doing so it keeps acetylcholine available within the synaptic cleft continuing to act on nicotinic and muscarinic receptors.
References
Physostigmine Pathway (new) References
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Pubmed: 9030575
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Pubmed: 7916667
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Pubmed: 8825633
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