Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
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cAMP-dependent protein kinase type II-beta regulatory subunit cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit D(2) dopamine receptor Adenylate cyclase type 2 Guanine nucleotide- binding protein G(s) subunit alpha isoforms short Guanine nucleotide- binding protein G(i) subunit alpha-1 Synaptic vesicular amine transporter Voltage- dependent calcium channel subunit alpha-2/delta-1 Voltage- dependent calcium channel subunit alpha-2/delta-2 Voltage- dependent N-type calcium channel subunit alpha-1B Sodium- dependent dopamine transporter Tyrosine 3-monooxygenase Aromatic-L- amino-acid decarboxylase cAMP Ca+ Dopamine Dopamine Apomorphine Dopamine Ca+ Apomorphine Apomorphine L-Tyrosine L-Dopa CO2 ATP PPi Na+ Na+ Fe2+ Pyridoxal 5'-phosphate Magnesium Activation of D2 dopamine receptors activates the Gi signalling cascade which leads to increased cAMP. Locomotor control Apomorphine is an agonist at D2, D3 and D4 receptors Presynaptic Neuron Cytosol Synaptic Vesicle Postsynaptic Neuron Cytosol Dopamine is produced in the Ventral Tegmental Area of the brain Caudate-putamen Synapse Blood vessel - Blood Brain Barrier Brain passive diffusion Apomorphine is taken sublingually
PRKAR2B PRKACA PRKACB PRKAR1A PRKACG PRKAR1B PRKAR2A DRD2 ADCY2 GNAS GNAI1 SLC18A2 CACNA2D1 CACNA2D2 CACNA1B SLC6A3 TH DDC cAMP Calcium Dopamine Dopamine Apomorphine Dopamine Calcium Apomorphine Apomorphine L-Tyrosine L-Dopa Carbon dioxide Adenosine triphosphate Pyrophosphate Sodium Sodium
PRKAR2B PRKACA PRKACB PRKAR1A PRKACG PRKAR1B PRKAR2A DRD2 ADCY2 GNAS GNAI1 SLC18A2 CACNA2D1 CACNA2D2 CACNA1B SLC6A3 TH DDC cAMP Ca+ LDP LDP VR004 LDP Ca+ VR004 VR004 Tyr L-Dopa CO2 ATP PPi Na+ Na+ Fe2+ Pyr-5'P Mg2+ Activation of D2 dopamine receptors activates the Gi signalling cascade which leads to increased cAMP. Locomotor control Apomorphine is an agonist at D2, D3 and D4 receptors Presynaptic Neuron Cytosol Synaptic Vesicle Postsynaptic Neuron Cytosol Dopamine is produced in the Ventral Tegmental Area of the brain Caudate-putamen Synapse Blood vessel - Blood Brain Barrier Brain passive diffusion Apomorphine is taken sublingually