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Abciximab
Cystatin-B
Amino acids
Bowman's Capsule
Proximal Tubule
Loop of Henle
Distal Tubule
Collecting Duct
Abciximab is metabolized by
the kidney, through
glomerular filtration and
extensive reactions that
leads to either reabsorption
or elimination of the
byproducts
Majority is broken down by
proteases that are found
throughout the kidney
filtration system. Targeting
majority of the Abciximab in
the proximal tubule
Glomerulus
Lumen
Blood
The fragments of Abciximab
are reduced to amino acids,
which are then reabsorbed
via the collecting duct to
be used in de novo protein
synthesis and other
metabolic pathways. All
additional byproducts in
excess is excreted via urine
Kidney
Unknown
CSTB
Amino acids
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Pathway Description
Abciximab Drug Metabolism
Homo sapiens
Metabolic Pathway
Created: 2023-09-14
Last Updated: 2024-01-20
References
Abciximab Drug Metabolism References
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Abciximab
Cystatin-B
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Abciximab
Cystatin-B
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