SMPDB

Pathway Description

Zalcitabine Predicted Metabolism Pathway

Homo sapiens

Metabolic Pathway

Created: 2023-12-04

Last Updated: 2024-02-03

Metabolites of Zalcitabine are predicted with biotransformer.

References

Zalcitabine Predicted Metabolism Pathway References

Wishart DS, Tian S, Allen D, Oler E, Peters H, Lui VW, Gautam V, Djoumbou-Feunang Y, Greiner R, Metz TO: BioTransformer 3.0-a web server for accurately predicting metabolic transformation products. Nucleic Acids Res. 2022 Jul 5;50(W1):W115-W123. doi: 10.1093/nar/gkac313.

Pubmed: 35536252

Ikeya K, Jaiswal AK, Owens RA, Jones JE, Nebert DW, Kimura S: Human CYP1A2: sequence, gene structure, comparison with the mouse and rat orthologous gene, and differences in liver 1A2 mRNA expression. Mol Endocrinol. 1989 Sep;3(9):1399-408. doi: 10.1210/mend-3-9-1399.

Pubmed: 2575218

Jaiswal AK, Nebert DW, Gonzalez FJ: Human P3(450): cDNA and complete amino acid sequence. Nucleic Acids Res. 1986 Aug 26;14(16):6773-4. doi: 10.1093/nar/14.16.6773.

Pubmed: 3755823

Quattrochi LC, Pendurthi UR, Okino ST, Potenza C, Tukey RH: Human cytochrome P-450 4 mRNA and gene: part of a multigene family that contains Alu sequences in its mRNA. Proc Natl Acad Sci U S A. 1986 Sep;83(18):6731-5. doi: 10.1073/pnas.83.18.6731.

Pubmed: 3462722

Highlighted elements will appear in red.

Highlight Compounds

	Heme
	Zalcitabine
	Zalcitabine PIS1M1
	Zalcitabine PIS1M2

Highlight Proteins

	Cytochrome P450 1A2
	Unknown

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