SMPDB

Showing 81 - 90 of 605359 pathways

SMPDB ID	Pathway Name and Description	Pathway Class	Chemical Compounds	Proteins
SMP0129802 View Pathway	Zanidatamab Drug Metabolism BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolic		Cystatin-B Zanidatamab
SMP0143007 View Pathway	Zanamivir Drug Metabolism Action Pathway BioPAX SVG SBGN SBML PWML All files (.zip)	Drug Action	Zanamivir
SMP0126040 View Pathway	Zanamivir Action Pathway Zanamivir, also known as Relenza, is an inhibitor of the viral neuraminidase protein. This antiviral is used to treat and prevent influenza A and B infections. By interacting with the neuraminidase, Zabamivir renders the influenza virus unable to escape its host cell. Neuraminidases are essential for the cleaving of the terminal sialic acids on the glycosylated HA during the virus budding to facilitate its release. In consequence, the virus will not be able to infect other cells. This molecule is available as an intravenous solution or as a powder for inhalation. BioPAX SVG SBGN SBML PWML All files (.zip)	Drug Action	Calcium Manganese N-Acetylneuraminic acid Zanamivir	Hemagglutinin Matrix protein 2 Neuraminidase Non-structural protein 1 Nuclear export protein Nucleoprotein Polymerase acidic protein Polymerase basic protein 2 RNA-directed RNA polymerase ca... ( show all show less )
SMP0130189 View Pathway	Zampilimab Drug Metabolism BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolic		Cystatin-B Zampilimab
SMP0129019 View Pathway	Zalutumumab Drug Metabolism BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolic		Cystatin-B Zalutumumab
SMP0129891 View Pathway	Zalifrelimab Drug Metabolism BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolic		Cystatin-B Zalifrelimab
SMP0143392 View Pathway	Zaleplon Drug Metabolism Action Pathway BioPAX SVG SBGN SBML PWML All files (.zip)	Drug Action	Zaleplon
SMP0126830 View Pathway	Zaleplon Action Pathway Zaleplon, a nonbenzodiazepine hypnotic from the pyrazolopyrimidine class, serves as a sedative used for the short-term treatment of insomnia in adults. Functioning within the gamma-aminobutyric acid-benzodiazepine (GABABZ) receptor complex, it shares certain pharmacological attributes with benzodiazepines despite its distinct chemical structure. Classified as a schedule IV drug in the United States, Zaleplon interacts with the CNS GABAA-receptor chloride ionophore complex at benzodiazepine (BZ) omega-1 (BZ1, ο1) receptors. Its mechanism of action involves subunit modulation of the GABABZ receptor chloride channel macromolecular complex, and it also selectively binds to the brain omega-1 receptor found on the alpha subunit of the GABA-A/chloride ion channel receptor complex, enhancing t-butyl-bicyclophosphorothionate (TBPS) binding. Zaleplon, distinctly separate from benzodiazepines and other hypnotic agents, effectively addresses short-term insomnia by interacting with these receptor systems. BioPAX SVG SBGN SBML PWML All files (.zip)	Drug Action	Adenosine triphosphate Calcium cAMP Carbon dioxide Chloride ion L-Glutamic acid Magnesium Pyridoxal 5'-phosphate Pyrophosphate Zaleplon γ-Aminobutyric acid ( show all show less )	Adenylate cyclase type 1 Gamma-aminobutyric acid recept... Gamma-aminobutyric acid recept... Gamma-aminobutyric acid recept... Gamma-aminobutyric acid type B... Gamma-aminobutyric acid type B... Glutamate decarboxylase 1 Vesicular inhibitory amino aci... Voltage-dependent P/Q-type cal... ( show all show less )
SMP0174633 View Pathway	Zalcitabine Predicted Metabolism Pathway Metabolites of Zalcitabine are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolic	Heme Zalcitabine Zalcitabine PIS1M1 Zalcitabine PIS1M2	Cytochrome P450 1A2 Unknown
SMP0143375 View Pathway	Zalcitabine Drug Metabolism Action Pathway BioPAX SVG SBGN SBML PWML All files (.zip)	Drug Action	Zalcitabine