Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
Loader

Loading Pathway...

Gamma- aminobutyric acid type B receptor Voltage- dependent T-type calcium channel subunit alpha-1H Voltage- dependent T-type calcium channel subunit alpha-1G Adenylate cyclase type 1 Vesicular inhibitory amino acid transporter Voltage- dependent P/Q-type calcium channel subunit alpha-1A Glutamate decarboxylase 1 γ-Aminobutyric acid cAMP γ-Aminobutyric acid Ca+ Trimethadione L-Glutamic acid γ-Aminobutyric acid Ca+ Ca+ Ca+ Trimethadione Trimethadione CO2 ATP PPi Magnesium Pyridoxal 5'-phosphate Gi/o signalling Glutamate Metabolism Hyperpolarization Hyperpolarization leading to reduced depolarization and excitability Presynaptic Neuron Post Synaptic Neuron Synaptic Vesicle Cytosol Cytosol Synapse Trimethadione binds to T-type calcium channels and inhibits calcium influx Hyperpolarization prevents absence seizures GABA release is inhibited due to mutations of the SCN1A, SCN1B gene causing enhanced reuptake Trimethadione is administered as an oral tablet
GABBR2 CACNA1H CACNA1G ADCY1 SLC32A1 CACNA1A GAD1 γ-Aminobutyric acid cAMP γ-Aminobutyric acid Calcium Trimethadione L-Glutamic acid γ-Aminobutyric acid Calcium Calcium Calcium Trimethadione Trimethadione Carbon dioxide Adenosine triphosphate Pyrophosphate Gi/o signalling Glutamate Metabolism Hyperpolarization
GABBR2 CACNA1H CACNA1G ADCY1 SLC32A1 CACNA1A GAD1 GABA cAMP GABA Ca+ Tridion Glu GABA Ca+ Ca+ Ca+ Tridion Tridion CO2 ATP PPi Mg2+ Pyr-5'P Gi/ sig PW000003 Hyper Hyperpolarization leading to reduced depolarization and excitability Presynaptic Neuron Post Synaptic Neuron Synaptic Vesicle Cytosol Cytosol Synapse Trimethadione binds to T-type calcium channels and inhibits calcium influx Hyperpolarization prevents absence seizures GABA release is inhibited due to mutations of the SCN1A, SCN1B gene causing enhanced reuptake Trimethadione is administered as an oral tablet
GABBR2 CACNA1H CACNA1G ADCY1 SLC32A1 CACNA1A GAD1 GABA cAMP GABA Ca2+ Tridion Glu GABA Ca2+ Ca2+ Ca2+ Tridion Tridion CO2 ATP Ppi Gi/ sig PW000003 Hyper